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ea0031p336 | Steroids | SFEBES2013

Reversal of dilated cardiomyopathy in a patient with Cushing’s syndrome after a successful adrenalectomy

Abbas Nadeem , Chambers John , Powrie J K

Cushings syndrome (CS) associated with dilated cardiomyopathy without LVH is rare but important to recognise as treatment of CS can lead to total recovery of heart function.A 30-year-old previously fit and well Turkish man presented with chest pain and was diagnosed with NSTEMI and CCF. An MRI of the heart and CT coronary angiogram showed normal coronary arteries but a large right adrenal tumour of 11.5 cm with extension into IVC. The transthoracic...

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ea0038p315 | Pituitary | SFEBES2015

Expression of MGMT in a large series of pituitary adenomas: lactotroph and corticotroph adenomas are more likely to be MGMT-negative than somatotroph and gonadotroph adenomas

Dixon Danielle A , Xekouki Paraskevi , Salaris Paola , Mustafa Omar , Prague Julia , Abbas Nadeem , Whitelaw Benjamin , Bodi Istvan , Aylwin Simon J B

Background: Lack of expression of MGMT (O-6-methylguanine-DNA methyltransferase) is associated with a better tumour response to temozolomide. There are no systematic studies of MGMT expression in pituitary tumour series.Aim: We introduced MGMT immunohistochemistry for all pituitary adenoma specimens in 2011. In this study we investigated the immunohistochemical expression of MGMT in a large series of pituitary adenomas, in order to determine (1) the over...

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Endocrine Abstracts

Reversal of dilated cardiomyopathy in a patient with Cushing’s syndrome after a successful adrenalectomy

Expression of MGMT in a large series of pituitary adenomas: lactotroph and corticotroph adenomas are more likely to be MGMT-negative than somatotroph and gonadotroph adenomas

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